|The diversity of the effects of sulfur mustard gas inhalation on respiratory system 10 years after a single, heavy exposure: analysis of 197 cases.|
|PMID: 9315808 Owner: NLM Status: MEDLINE|
|OBJECTIVE: To find out the late pulmonary sequelae of sulfur mustard gas inhalation in 197 veterans, 10 years after their exposure. DESIGN: Cross-sectional clinical study. SETTING: University hospital. PATIENTS: One hundred ninety-seven veterans with a single, heavy exposure to sulfur mustard gas in 1986 and 86 nonexposed veterans as their control group. INTERVENTIONS: Pulmonary function tests, carbon monoxide diffusion capacity, bronchoscopy, and high-resolution CT of the chest were performed in all patients. Transbronchial lung biopsy was done in 24 suspected cases of pulmonary fibrosis. RESULTS: Asthma was diagnosed in 21 (10.65%), chronic bronchitis in 116 (58.88%), bronchiectasis in 17 (8.62%), airway narrowing due to searing or granulation tissue in 19 (9.64%), and pulmonary fibrosis in 24 (12.18%) cases. None of these were found among the control group except for a single case of chronic bronchitis. CONCLUSION: Although the respiratory symptoms of an acute sulfur mustard gas inhalation are usually transient and nonspecific, it can lead to the development of a series of chronic destructive pulmonary sequelae in such cases.|
|A Emad; G R Rezaian|
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|Type: Journal Article|
|Title: Chest Volume: 112 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1997 Sep|
|Created Date: 1997-10-22 Completed Date: 1997-10-22 Revised Date: 2004-11-17|
Medline Journal Info:
|Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES|
|Languages: eng Pagination: 734-8 Citation Subset: AIM; IM|
|Department of Internal Medicine, Shiraz University of Medical Sciences, Iran.|
|APA/MLA Format Download EndNote Download BibTex|
Airway Obstruction / chemically induced
Asthma / chemically induced
Bronchiectasis / chemically induced
Bronchitis / chemically induced
Carbon Monoxide / diagnostic use
Chemical Warfare Agents / adverse effects*
Cicatrix / chemically induced
Forced Expiratory Volume / drug effects
Granulation Tissue / drug effects, pathology
Lung / drug effects*, pathology, radiography
Mustard Gas / adverse effects*
Peak Expiratory Flow Rate / drug effects
Pulmonary Diffusing Capacity / drug effects
Pulmonary Fibrosis / chemically induced, pathology
Respiratory Function Tests
Tomography, X-Ray Computed
Vital Capacity / drug effects
|0/Chemical Warfare Agents; 505-60-2/Mustard Gas; 630-08-0/Carbon Monoxide|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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