| A disturbance of gastric function in bulimia nervosa. | |
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MedLine Citation:
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PMID: 14573321 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Because the stomach plays an important role in the development of satiety, gastric function was examined in bulimia nervosa (BN). METHODS: Sixteen patients with BN and 16 controls swallowed an inflatable bag, which was positioned in the proximal stomach. Minimal distending pressure (MDP), the pressure needed to overcome intraabdominal pressure, was determined. Gastric volume was recorded after subjects drank a liquid meal. RESULTS: MDP was similar in patient and control groups (7.56 +/- 2.13 vs. 7.13 +/- 2.06 mmHg; t =.57, df = 30, p =.58). Average postmeal gastric relaxation was significantly lower in the patient group (29.7 +/- 97.8 vs. 105.1 +/- 103.3 mL; t = 2.13, df = 30, p =.042). CONCLUSIONS: Stomach relaxation following food consumption is significantly diminished in patients with BN. Physiologic abnormalities of stomach function in BN may contribute to the perpetuation of disturbances in behavior in this disorder. |
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Authors:
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B Timothy Walsh; Ellen Zimmerli; Michael J Devlin; Janet Guss; Harry R Kissileff |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Biological psychiatry Volume: 54 ISSN: 0006-3223 ISO Abbreviation: Biol. Psychiatry Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-10-23 Completed Date: 2003-11-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0213264 Medline TA: Biol Psychiatry Country: United States |
Other Details:
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Languages: eng Pagination: 929-33 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bulimia / physiopathology* Case-Control Studies Female Humans Pressure Stomach / physiopathology* |
| Grant Support | |
ID/Acronym/Agency:
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MH42206/MH/NIMH NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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