Document Detail


The distribution of uterine glycogen during early pregnancy in the young and senescent golden hamster.
MedLine Citation:
PMID:  1168217     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Glycogen distribution in the uterus of young and old hamsters was examined histochemically during the implantation of the embryo. Decidual cells and glycogen first appeared at 96 hours (post-ovulation) in the young animal. Decidualization did not occur in the senescent animal until 108 hours of development and the appearance of glycogen in the antimesometrial stroma was further delayed until 120 hours of development in the aged female. By 132 hours glycogen synthesis in the antimesometrial decidua was similar in both groups. Mesometrial glycogen synthesis in the aged animal continued to lag behind that of the young animal throughout the period investigated. The role of the delayed decidual cell response and the appearance of glycogen as possible causal factors in the observed decreased reproductive output in senescent animals is discussed.
Authors:
L W Thorpe; T J Connors
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of gerontology     Volume:  30     ISSN:  0022-1422     ISO Abbreviation:  J Gerontol     Publication Date:  1975 Mar 
Date Detail:
Created Date:  1975-07-03     Completed Date:  1975-07-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374762     Medline TA:  J Gerontol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  149-53     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cricetinae
Decidua / metabolism
Embryo Implantation
Female
Glucagon / biosynthesis
Histocytochemistry
Humans
Maternal Age*
Pregnancy
Pregnancy, Animal*
Time Factors
Uterus / metabolism*
Chemical
Reg. No./Substance:
9007-92-5/Glucagon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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