Document Detail

The distribution of marked dermal cells from small localized implants in limb regenerates.
MedLine Citation:
PMID:  6389219     Owner:  NLM     Status:  MEDLINE    
Numerous experiments have demonstrated that skin has a profound influence on the pattern of limb regeneration in urodeles. In this investigation, the fate during regeneration of marked cells derived from narrow strips of skin inserted into different positions around the limb circumference has been followed. Skin strips were taken from triploid axolotls and transplanted into diploid sibling animals. The distribution of trinucleolate cells was determined at the site of amputation and in the regenerated limb. The results indicate that at the time of amputation marked cells appear to be localized to the graft, whereas in the regenerated marked cells may be found at all proximal-distal levels and at any position around the circumference of the limb. These results are discussed in terms of a possible mechanism for distal outgrowth.
C Rollman-Dinsmore; S V Bryant
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Developmental biology     Volume:  106     ISSN:  0012-1606     ISO Abbreviation:  Dev. Biol.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-01-23     Completed Date:  1985-01-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372762     Medline TA:  Dev Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  275-81     Citation Subset:  IM    
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MeSH Terms
Forelimb / physiology*
Skin / cytology
Skin Transplantation*
Grant Support

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