Document Detail


The distribution of genetic parameter estimates and confidence intervals from small disconnected diallels.
MedLine Citation:
PMID:  15754206     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The distributions of genetic variance components and their ratios (heritability and type-B genetic correlation) from 105 pairs of six-parent disconnected half-diallels of a breeding population of loblolly pine (Pinus taeda L.) were examined. A series of simulations based on these estimates were carried out to study the coverage accuracy of confidence intervals based on the usual t-method and several other alternative methods. Genetic variance estimates fluctuated greatly from one experiment to another. Both general combining ability variance (sigma(2) (g)) and specific combining ability variance (sigma(2) (s)) had a large positive skewness. For sigma(2) (g) and sigma(2) (s), a skewness-adjusted t-method proposed by Boos and Hughes-Oliver (Am Stat 54:121-128, 2000) provided better upper endpoint confidence intervals than t-intervals, whereas they were similar for the lower endpoint. Bootstrap BCa-intervals (Efron and Tibshirani, An introduction to the bootstrap. Chapman & Hall, London 436 p, 1993) and Hall's transformation methods (Zhou and Gao, Am Stat 54:100-104, 2000) had poor coverages. Coverage accuracy of Fieller's interval endpoint(J R Stat Soc Ser B 16:175-185, 1954) and t-interval endpoint were similar for both h(2) and r(B) for sample sizes n</=10, but for n=30 the Fieller's method is much better.
Authors:
Fikret Isik; Dennis D Boos; Bailian Li
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2005-03-08
Journal Detail:
Title:  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik     Volume:  110     ISSN:  0040-5752     ISO Abbreviation:  Theor. Appl. Genet.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-05-02     Completed Date:  2005-07-28     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  0145600     Medline TA:  Theor Appl Genet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1236-43     Citation Subset:  IM    
Affiliation:
Department of Forestry and Environmental Resources, North Carolina State University, Campus Box 8002, Raleigh, NC 27695, USA. fisik@ncsu.edu
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Breeding / methods*
Computer Simulation
Confidence Intervals*
Data Interpretation, Statistical*
Pinus taeda / genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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