| The distinct morphogenic states of Candida albicans. | |
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MedLine Citation:
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PMID: 15223059 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The human fungal pathogen, Candida albicans can grow in at least three different morphologies: yeast, pseudohyphae and hyphae. Further morphological forms exist during colony switching, for example, opaque phase cells are oblong, rather than the oval shape of yeast cells. Pseudohyphae and hyphae are both elongated and sometimes there has been little attempt to distinguish between them, as both are "filamentous forms" of the fungus. We review here the differences between them that suggest that they are distinct morphological states. We argue that studies on "filamentous forms" should always include a formal analysis to determine whether the cells are hyphae or pseudohyphae and we suggest some simple experimental criteria that can be applied to achieve this. |
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Authors:
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Peter Sudbery; Neil Gow; Judith Berman |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Trends in microbiology Volume: 12 ISSN: 0966-842X ISO Abbreviation: Trends Microbiol. Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-06-29 Completed Date: 2004-10-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9310916 Medline TA: Trends Microbiol Country: England |
Other Details:
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Languages: eng Pagination: 317-24 Citation Subset: IM |
Affiliation:
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Sheffield University, Department of Molecular Biology and Biotechnology, Western Bank, Sheffield S10 2TN, UK. P.Sudbery@shef.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Candida albicans
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cytology*,
genetics,
growth & development*,
physiology Cell Cycle Fungal Proteins / genetics, physiology Gene Expression Regulation, Fungal* Genes, Fungal Hyphae / genetics, growth & development, physiology Morphogenesis Yeasts / genetics, growth & development, physiology |
| Chemical | |
Reg. No./Substance:
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0/Fungal Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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