Document Detail


Behçet's disease in Moroccan children: a report of 12 cases.
MedLine Citation:
PMID:  15513688     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report 12 cases of Behçet's disease (BD) in children. The mean age of symptom onset was 12.4 years. Four patients (33.3%) had a past familial history of BD. Clinical manifestations were: oral aphtosis (n = 12), genital aphtosis (n = 9), ocular involvement (n = 9), neuro-Behçet (n = 6), venous thrombosis (n = 4), articular involvement (n = 3), and entero-Behçet (n = 1). All patients but one were initially treated with steroids; three cases with ocular involvement were treated with chlorambucil; and three other cases of neuro-Behçet were treated with cyclophosphamide. After a mean follow-up of 4 years, four patients with neurological involvement developed steroid-dependence with recurrence of symptoms. Four patients had optic atrophy with blindness.
Authors:
F Allali; A Benomar; A Karim; N Lazrak; Z Mohcine; M El Yahyaoui; T Chkili; N Hajjaj-Hassouni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of rheumatology     Volume:  33     ISSN:  0300-9742     ISO Abbreviation:  Scand. J. Rheumatol.     Publication Date:  2004  
Date Detail:
Created Date:  2004-10-29     Completed Date:  2004-12-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0321213     Medline TA:  Scand J Rheumatol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  362-3     Citation Subset:  IM    
Affiliation:
Rheumatology B Department, El Ayachi Hospital, Sale, Morocco. fadouaallali@yahoo.fr
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Behcet Syndrome / classification,  diagnosis*,  genetics*
Child
Female
Humans
Male
Morocco
Nuclear Family
Retrospective Studies

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