Document Detail

Behçet's disease and cardiovascular involvement.
MedLine Citation:
PMID:  16218475     Owner:  NLM     Status:  MEDLINE    
Behcet's disease (BD) is a multisystem disease of unknown etiology characterized by chronic relapsing orogenital ulcers, uveitis and systemic involvement including articular, gastrointestinal, cardiopulmonary, neurological and vascular pathology. The incidence and nature of cardiac involvement are not clearly elucidated. Cardiovascular manifestations have been reported in 7-46% of patients and mortality occurs in up to 20% of those patients with marked vascular involvement. Sporadic cases of endocarditis, myocarditis, pericarditis, acute myocardial infarction, aortic aneurysm, ventricular thrombosis, congestive cardiomyopathy and valvular dysfunction have been reported. This review discusses the general aspects of the pathogenic mechanisms and clinical features cardiovascular involvement in BD, and provides the data of cardiovascular involvement in a cohort of Italian BD patients.
F Atzeni; P Sarzi-Puttini; A Doria; L Boiardi; N Pipitone; C Salvarani
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Lupus     Volume:  14     ISSN:  0961-2033     ISO Abbreviation:  Lupus     Publication Date:  2005  
Date Detail:
Created Date:  2005-10-12     Completed Date:  2005-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  England    
Other Details:
Languages:  eng     Pagination:  723-6     Citation Subset:  IM    
Rheumatology Unit, L Sacco University Hospital, Milan, Italy.
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MeSH Terms
Behcet Syndrome* / complications,  pathology,  physiopathology
Cardiovascular Diseases* / etiology,  pathology,  physiopathology
Heart / anatomy & histology,  physiopathology
Myocardium / pathology*

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