Document Detail


The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).
MedLine Citation:
PMID:  21764305     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A summary of the discovery and advancement of inhibitors of fatty acid amide hydrolase (FAAH) is presented.
Authors:
Katerina Otrubova; Cyrine Ezzili; Dale L Boger
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2011-06-28
Journal Detail:
Title:  Bioorganic & medicinal chemistry letters     Volume:  21     ISSN:  1464-3405     ISO Abbreviation:  Bioorg. Med. Chem. Lett.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-29     Completed Date:  2011-11-22     Revised Date:  2014-09-13    
Medline Journal Info:
Nlm Unique ID:  9107377     Medline TA:  Bioorg Med Chem Lett     Country:  England    
Other Details:
Languages:  eng     Pagination:  4674-85     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Amidohydrolases / antagonists & inhibitors*
Animals
Drug Discovery*
Enzyme Inhibitors / chemical synthesis,  chemistry,  pharmacology*
Humans
Molecular Structure
Stereoisomerism
Structure-Activity Relationship
Grant Support
ID/Acronym/Agency:
DA015648/DA/NIDA NIH HHS; R01 DA015648/DA/NIDA NIH HHS; R01 DA015648-07/DA/NIDA NIH HHS
Chemical
Reg. No./Substance:
0/Enzyme Inhibitors; EC 3.5.-/Amidohydrolases; EC 3.5.1.-/fatty-acid amide hydrolase
Comments/Corrections

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