| The directional reflectance of the retinal nerve fiber layer of the toad. | |
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MedLine Citation:
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PMID: 1639607 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Various optical methods for assessing the retinal nerve fiber layer (RNFL) depend on reflected light, but little is known about the characteristics of the RNFL as a reflecting structure. The authors investigated the angular dependence of light reflected by the unmyelinated nerve fibers of the toad eyecup using a small 500-nm light source that could illuminate the retina from various directions and a movable low-power microscope that imaged the retina onto a cooled charge-coupled device in a digital camera system. Measured areas had nerve fiber bundles separated by gaps. Therefore, the reflectance of a bundle alone could be determined from the difference in intensity between the bundle and an adjacent gap. The RNFL reflectance showed striking directional dependence; nerve fiber bundles seen when illuminated from one direction disappeared completely when illuminated from another. Light reflected by a bundle was confined to a conical sheet concentric with the axis of the bundle. The apex angle of the cone was twice the angle between the incident light and the bundle axis, and the orientation of the cone changed with the orientation of the RNFL. This behavior was consistent with the theory of light scattering by cylinders. Therefore, it was concluded that the RNFL reflectance arises from cylindric structures. These results have clinical significance for imaging the RNFL in the human eye because the apparent intensity of the RNFL will depend, not just on its thickness, but also on its orientation relative to the imaging system. |
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Authors:
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R W Knighton; C Baverez; A Bhattacharya |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Investigative ophthalmology & visual science Volume: 33 ISSN: 0146-0404 ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-08-31 Completed Date: 1992-08-31 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2603-11 Citation Subset: IM |
Affiliation:
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Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, FL 33101. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bufo marinus Fundus Oculi Light* Nerve Fibers / physiology* Photography Retina / cytology, physiology* Scattering, Radiation |
| Grant Support | |
ID/Acronym/Agency:
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EY02180/EY/NEI NIH HHS; EY08684/EY/NEI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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