| A direct macrophage migration inhibition test applied in man. | |
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MedLine Citation:
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PMID: 59649 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A direct macrophage migration test is described, which proved to be useful for the detection of cellular hypersensitivity in man. We used a modification of the method described by Hughes & Paty (1972). In this method the MLR is abolished by 100 rad gamma-irradiation of the peritoneal exudate cells prior to pooling with human lymphocytes. Experiments with various intensity of irradiation, PPD, muscle antigen and encephalitogenic factor were performed to check this method. In a pilot study lymphocytes of patients with diseases of the central or peripheral nervous system or of muscle were tested. This proved that a hypersensitivity of Ef was present in various diseases of the CNS, while in muscle diseases positive tests were found using muscle antigen. |
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Authors:
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A W Teelken; J M Minderhoud |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical and experimental immunology Volume: 24 ISSN: 0009-9104 ISO Abbreviation: Clin. Exp. Immunol. Publication Date: 1976 Apr |
Date Detail:
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Created Date: 1976-10-02 Completed Date: 1976-10-02 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0057202 Medline TA: Clin Exp Immunol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 26-32 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antigens Ascitic Fluid / immunology, radiation effects Cell Migration Inhibition* Central Nervous System Diseases / immunology Gamma Rays Humans Immunity, Cellular Lymphocyte Culture Test, Mixed Lymphocytes / immunology Macrophages / immunology*, radiation effects Muscles / immunology Muscular Diseases / immunology Myelin Basic Proteins / immunology Peripheral Nervous System Diseases / immunology Radiation Effects Tuberculin Tuberculin Test |
| Chemical | |
Reg. No./Substance:
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0/Antigens; 0/Myelin Basic Proteins; 0/Tuberculin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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