| A direct approach to the study of the effect of gravity on axis formation in birds. | |
| | |
MedLine Citation:
|
PMID: 11537926 Owner: NASA Status: MEDLINE |
Abstract/OtherAbstract:
|
A system has been developed to enable the normal development of aborted very early uterine avian embryos, outside the female's uterus. The shell-less aborted egg was put into a foster shell of a sister egg, previously laid by the same female. The empty space between the shell and aborted egg was filled with artificial uterine fluid. The reconstructed eggs were incubated at 42 degrees C for 30 hours in a vertical position. The atmosphere contained a high concentration of CO2 (8-10%). At the termination of the 30 h the eggs were transferred to incubation at 37 degrees C in normal atmospheric conditions. Normal development has been recorded for a certain percentage of eggs incubated up to 12 days. In other cases abnormalities, arrested development or development of extraembryonic membranes only, without a sign of an embryonic axis, have been observed. The three important conclusions from the above experiments were: 1. It is possible to develop a closed, self-contained system, disconnected from the female's body, that would support the development of early uterine embryos. 2. The incidence of embryo-less extraembryonic membranes in such a system, is correlated with the degree of detachment of the "yolk" from the outer envelopes. 3. Such a system can be further developed into an experiment suited for microgravity conditions which will be an alternative to an experiment with live birds. The experiment will be aimed at testing the importance of gravity in changing the radially symmetrical avian blastoderm into a bilaterally symmetrical blastoderm. |
| | |
Authors:
|
H Eyal-Giladi; M Goldberg; H Refael; O Avner |
Related Documents
:
|
23646746 - Influence of sintering temperature on the microstructure and thermoelectric properties ... 3598506 - Modelling heat and mass exchange of buried avian eggs. 23184946 - Monomeric synucleins generate membrane curvature. 3298536 - Trace element metabolism in the developing avian embryo: a review. 15890816 - Effects of increasing temperatures on physiological changes in pigs at different relati... 8125966 - Site-specific biotinylation of colicin ia. a probe for protein conformation in the memb... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Advances in space research : the official journal of the Committee on Space Research (COSPAR) Volume: 14 ISSN: 0273-1177 ISO Abbreviation: Adv Space Res Publication Date: 1994 |
Date Detail:
|
Created Date: 1995-07-05 Completed Date: 1995-07-05 Revised Date: 2007-08-01 |
Medline Journal Info:
|
Nlm Unique ID: 9878935 Medline TA: Adv Space Res Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 271-9 Citation Subset: S |
Affiliation:
|
Department of Cell and Animal Biology, Hebrew University of Jerusalem, Israel. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blastoderm / cytology, physiology* Cell Polarity Egg Shell / physiology Embryo, Nonmammalian / physiology Embryology / methods* Female Gravitation* Ovum / cytology*, growth & development, physiology Quail / embryology* Rotation Space Flight Time Factors Uterus / physiology Weightlessness Weightlessness Simulation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Xenopus laevis embryos can establish their spatial bilateral symmetrical body pattern without gravit...
Next Document: Teratogenic effects of gravitational changes.