Document Detail


Is digoxin a drug of the past?
MedLine Citation:
PMID:  16970134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Digoxin has been the cornerstone of the treatment of heart failure for more than 2 centuries. Now that newer therapies have been introduced that reduce the mortality rate in heart failure and recent trials have failed to prove the same for digoxin, its use has significantly decreased. But a careful review of the multiple pharmacologic actions of digoxin and closer analysis of the results of recent trials suggest that digoxin may in fact continue to be an effective treatment for heart failure.
Authors:
Mohammad Hassan Pervaiz; Michael G Dickinson; Mohamad Yamani
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cleveland Clinic journal of medicine     Volume:  73     ISSN:  0891-1150     ISO Abbreviation:  Cleve Clin J Med     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-14     Completed Date:  2006-10-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8703441     Medline TA:  Cleve Clin J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  821-4, 826, 829-32 passim     Citation Subset:  IM    
Affiliation:
Department of Medicine, Michigan State University, East Lansing 44824, USA. mohammad.pervaiz@ht.msu.edu
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MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / drug therapy
Cardiotonic Agents / therapeutic use*
Digoxin / therapeutic use*
Heart Failure / drug therapy*
Humans
Chemical
Reg. No./Substance:
0/Cardiotonic Agents; 20830-75-5/Digoxin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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