| The differential effect of altered auditory feedback on speech in early- and late-onset of Parkinson disease. | |
| | |
MedLine Citation:
|
PMID: 20331066 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Advanced speech symptoms in Parkinson disease (PD), such as "festinating speech" or palilalia and frequent hesitations, are a clinical challenge. This report is a part of a larger study testing the hypothesis that the use of altered auditory feedback (AAF) would improve speech intelligibility in patients with PD and more advanced speech impairment. Our initial report showed that the use of AAF indeed improved speech intelligibility in these patient's spontaneous speech [Wang et al. (2008)]. In this report, the spontaneous speech samples produced by four older-onset (aged 72.4 SD 6.02 years) vs four young-onset PD patients (aged 54.2 SD 4.44 years), with and without the use of AAF, were analyzed. The results indicated that, regardless of the use of AAF, the older-onset patients performed poorer than the young-onset patients in many areas including the mean length of utterance in words, number of different word roots, within utterance pause time, and words per minute. These findings are consistent with the report that patients with an older age at onset had more rapid progression of PD than those with a younger age at onset in mentation, freezing, and activities of daily living. Possible underlying mechanism for the findings will be discussed. |
| | |
Authors:
|
Emily Q Wang; Leo Verhagen Metman |
Related Documents
:
|
19550026 - Complexity analysis of eeg in patients with schizophrenia using fractal dimension. 14506716 - Late-onset distal muscular dystrophy affecting the posterior calves. 17509836 - Evidence of a latitudinal gradient in the age at onset of schizophrenia. 9309466 - A cognitive neuropsychological approach to the study of delusions in late-onset schizop... 12677736 - A morphometric consideration of nasal septal deviations by people with paranasal compla... 19900456 - Physiological suppression eases in damaraland mole-rat societies when ecological constr... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of the Acoustical Society of America Volume: 127 ISSN: 1520-8524 ISO Abbreviation: J. Acoust. Soc. Am. Publication Date: 2010 Mar |
Date Detail:
|
Created Date: 2010-03-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7503051 Medline TA: J Acoust Soc Am Country: United States |
Other Details:
|
Languages: eng Pagination: 1997 Citation Subset: IM |
Affiliation:
|
Dept. of Commun. Disord. and Sci., Rush Univ. Medical Ctr., 1653 West Congress Parkway, 203 SENN, Chicago, ILRush Univ. Medical Ctr., Chicago, IL. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Temporal analysis of simultaneous nasopharyngoscopic and nasometric recordings.
Next Document: Measuring speech and language characteristics of effects of medications on cognition.