Document Detail


The differential diagnosis between preeclamptic toxemia and glomerulonephritis in patients with proteinuria during pregnancy.
MedLine Citation:
PMID:  1005033     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The renal biopsies from 123 patients who presented with proteinuria during pregnancy have been reviewed. Forty-seven showed glomerulonephritis that could be diagnosed on morphological grounds or on a clear-cut history of urine abnormalities before pregnancy. Fifty of the remaining 76 had been followed after pregnancy. In these 50 patients, a retrospective diagnosis of glomerulonephritis or preeclamptic toxemia was based on the persistence or disappearance of proteinuria and/or hematuria three or more months after pregnancy. Among 22 in whom a biopsy diagnosis of "pure" preeclamptic toxemia had been made, 19 showed disappearance of urine abnormalities after pregnancy, thus confirming the biopsy diagnosis. A retrospective analysis showed focal and segmental glomeris group but none in the preeclamptic toxemia group. Other differences could not be defined without quantitative evaluation; however, the glomeruli appeared to be more cellular in the glomerulonephritis group. The presence of IgA, IgG, IgM, Complement, and fibrin was not of value in distinguishing glomerulonephritis from preeclamptic toxemia.
Authors:
P Kincaid-Smith; K F Fairley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Perspectives in nephrology and hypertension     Volume:  5     ISSN:  0092-2900     ISO Abbreviation:  Perspect Nephrol Hypertens     Publication Date:  1976  
Date Detail:
Created Date:  1977-02-24     Completed Date:  1977-02-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0402144     Medline TA:  Perspect Nephrol Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  157-67     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Arteries / pathology
Diagnosis, Differential
Female
Glomerulonephritis / complications,  diagnosis*
Humans
Kidney / blood supply,  pathology
Pre-Eclampsia / complications
Pregnancy
Pregnancy Complications / diagnosis*,  pathology
Proteinuria / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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