Document Detail


The diagnostic yield of exercise stress testing as a screening tool for subclinical coronary artery disease in patients with moderate to severe obstructive sleep apnea.
MedLine Citation:
PMID:  21344047     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY OBJECTIVE: To address the yield of routine exercise stress testing as a screening tool for subclinical coronary artery disease (CAD) in patients with moderate to severe obstructive sleep apnea (OSA).
DESIGN AND SETTING: A cross-sectional study in a university hospital.
PARTICIPANTS: Of 380 consecutive patients with OSA, data from 206 subjects (mean apnea-hypopnea index [AHI] 41 ± 21 events/h) were studied; data from 78 with a history of CAD and 96 with mild OSA (AHI 5-15 events/h) were excluded.
MEASUREMENTS: Routine exercise stress testing.
RESULTS: Six subjects could not reach maximal exercise capacity. Of the remaining 200 patients, the results of exercise stress testing were normal in 189. Three had a positive stress test, with coronary angiography confirming the diagnosis of CAD. Eight patients had suspected positive findings on the stress test, but the results of the myocardial perfusion study were negative.
CONCLUSION: The prevalence of subclinical CAD in this selected population with OSA was 1.5%, which is not higher than that in a general population. Our results do not support the routine use of exercise stress testing in patients with moderate to severe OSA who do not have symptoms of CAD.
Authors:
Aykut Cilli; Fulsen Batmaz; Ibrahim Demir; Adil Boz; Evren Toprak; Tülay Ozdemir; Yüksel Peker
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine     Volume:  7     ISSN:  1550-9397     ISO Abbreviation:  J Clin Sleep Med     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-23     Completed Date:  2011-07-13     Revised Date:  2011-08-25    
Medline Journal Info:
Nlm Unique ID:  101231977     Medline TA:  J Clin Sleep Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  25-9     Citation Subset:  IM    
Affiliation:
Department of Respiratory Diseases, Akdeniz University Hospital, Antalya, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Comorbidity
Coronary Angiography
Coronary Artery Disease / diagnosis*,  epidemiology*
Cross-Sectional Studies
Exercise Test
Female
Follow-Up Studies
Humans
Incidence
Male
Mass Screening / methods
Middle Aged
Polysomnography / methods
Reference Values
Risk Assessment
Severity of Illness Index
Sex Distribution
Sleep Apnea, Obstructive / diagnosis*,  epidemiology*
Comments/Corrections

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