Document Detail

Dexmedetomidine/ketamine for diagnostic cardiac catheterization in a child with idiopathic pulmonary hypertension.
MedLine Citation:
PMID:  19833278     Owner:  NLM     Status:  MEDLINE    
The use of a combination of dexmedetomidine and ketamine to provide procedural sedation in a 12-year old boy with a diagnosis of idopathic pulmonary hypertension and a behavioral disorder, undergoing diagnostic cardiac catheterization, is presented. Following a loading dose of ketamine one mg/kg and dexmedetomidine one mcg/kg, an infusion of dexmedetomidine at one mcg/kg/hr was used with the patient breathing spontaneously. Stable hemodynamics were observed throughout the procedure and pulmonary vascular resistance was measured under three conditions. The dexmedetomidine infusion was continued for two hours post-catheterization, facilitating a smooth emergence.
Hamish M Munro; Donald E Felix; David G Nykanen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical anesthesia     Volume:  21     ISSN:  1873-4529     ISO Abbreviation:  J Clin Anesth     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-10-16     Completed Date:  2010-01-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8812166     Medline TA:  J Clin Anesth     Country:  United States    
Other Details:
Languages:  eng     Pagination:  435-8     Citation Subset:  IM    
The Congenital Heart Institute, Arnold Palmer Hospital for Children, Orlando, FL 32806, USA.
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MeSH Terms
Anesthetics, Dissociative / therapeutic use
Dexmedetomidine / therapeutic use*
Drug Therapy, Combination
Heart Catheterization / methods*
Hemodynamics / drug effects
Hypertension, Pulmonary / diagnosis
Hypnotics and Sedatives / therapeutic use
Ketamine / therapeutic use*
Vascular Resistance / drug effects
Reg. No./Substance:
0/Anesthetics, Dissociative; 0/Hypnotics and Sedatives; 113775-47-6/Dexmedetomidine; 6740-88-1/Ketamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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