Document Detail


The diagnosis and treatment of the azoospermic patient in the age of intracytoplasmic sperm injection.
MedLine Citation:
PMID:  12516760     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Microsurgical reconstruction remains the treatment of choice for men with reconstructable obstructive azoospermia. Sperm retrieval techniques performed with ICSI are highly effective for men in whom reconstruction is not feasible. In men with nonobstructive azoospermia, the optimization of spermatogenesis with hormonal therapy and, when appropriate, microsurgical varicocelectomy can result in the appearance of adequate sperm in the ejaculate for ICSI. In men with persistent nonobstructive azoospermia, TESE with ICSI has provided encouraging results. Caution must be used when this ART is applied in couples in whom genetic aberrations are detected given certain inheritance of these anomalies, as the genetic consequences of this procedure have not been thoroughly elucidated. Just as the possibility of ICSI was thought to be inconceivable several decades ago, the advent of future sentinel discoveries will present the possibility for realization of achievements that now seem incredulous.
Authors:
Carin V Hopps; Marc Goldstein; Peter N Schlegel
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Urologic clinics of North America     Volume:  29     ISSN:  0094-0143     ISO Abbreviation:  Urol. Clin. North Am.     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2003-01-08     Completed Date:  2003-01-22     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0423221     Medline TA:  Urol Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  895-911     Citation Subset:  AIM; IM    
Affiliation:
Department of Urology, Cornell Institute for Reproductive Medicine, The New York Weill Cornell Medical Center, 525 East 68th Street, New York, NY 10021, USA.
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MeSH Terms
Descriptor/Qualifier:
Humans
Male
Oligospermia / diagnosis*,  etiology,  surgery*
Sperm Injections, Intracytoplasmic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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