| The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate. | |
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MedLine Citation:
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PMID: 19026340 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intraventricular hemorrhage (IVH) occurs in 20% to 25% of very low birthweight preterm neonates and may be associated with significant sequelae. Infants who have IVH are at risk for posthemorrhagic hydrocephalus and periventricular leukomalacia; as many as 75% of those who have parenchymal involvement of hemorrhage suffer significant neurodevelopmental disability. Because of the prevalence of IVH and the medical and societal impact of this disease, many postnatal pharmacologic prevention strategies have been explored. Randomized clinical prevention trials should provide long-term neurodevelopmental follow-up to assess the impact of preterm birth, injury, and pharmacologic intervention on the developing brain. |
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Authors:
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Heather J McCrea; Laura R Ment |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Clinics in perinatology Volume: 35 ISSN: 1557-9840 ISO Abbreviation: Clin Perinatol Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-25 Completed Date: 2009-03-10 Revised Date: 2011-09-26 |
Medline Journal Info:
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Nlm Unique ID: 7501306 Medline TA: Clin Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 777-92, vii Citation Subset: IM |
Affiliation:
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Yale University School of Medicine, New Haven, CT 06510, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Hemorrhage
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complications,
diagnosis*,
physiopathology,
prevention & control* Cerebral Ventricles / blood supply* Coagulants / therapeutic use Cyclooxygenase Inhibitors / therapeutic use Factor VIIa / therapeutic use Humans Ibuprofen / therapeutic use Indomethacin / therapeutic use Infant, Newborn Infant, Premature* Phenobarbital / therapeutic use |
| Grant Support | |
ID/Acronym/Agency:
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NS 27116/NS/NINDS NIH HHS; NS 53865/NS/NINDS NIH HHS; R01 NS027116-19/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Coagulants; 0/Cyclooxygenase Inhibitors; 15687-27-1/Ibuprofen; 50-06-6/Phenobarbital; 53-86-1/Indomethacin; EC 3.4.21.21/Factor VIIa |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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