Document Detail

The diagnosis and management of egg allergy.
MedLine Citation:
PMID:  16566865     Owner:  NLM     Status:  MEDLINE    
Egg allergy is a common food hypersensitivity in children. Atopic dermatitis represents the main clinical manifestation in infancy. On first exposure, many of these infants present with urticaria, angioedema, or anaphylaxis. The role of egg allergy in gastrointestinal conditions is less well understood. The "gold standard" for the diagnosis of egg allergy is the double-blind, placebo-controlled food challenge. Diagnostic cut-off levels have been defined for food-specific serum immunoglobulin E antibody level and skin prick test wheal diameter that predict an adverse challenge outcome. This has significantly reduced the need for formal food challenges. Atopy patch testing, in conjunction with immunoglobulin E-based tests, may further improve the accuracy of predicting a positive challenge. The treatment of egg allergy consists of dietary elimination, or a maternal elimination diet in breast-fed infants. Approximately two thirds of infants with egg allergy will become tolerant by 7 years of age.
Ralf G Heine; Nora Laske; David J Hill
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current allergy and asthma reports     Volume:  6     ISSN:  1529-7322     ISO Abbreviation:  Curr Allergy Asthma Rep     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-03-28     Completed Date:  2006-09-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101096440     Medline TA:  Curr Allergy Asthma Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  145-52     Citation Subset:  IM    
Department of Allergy, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia.
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MeSH Terms
Asthma / etiology
Dermatitis, Atopic / etiology
Egg Hypersensitivity / diagnosis*,  therapy
Gastrointestinal Diseases / etiology
Immunoglobulin E / blood
Milk, Human / immunology
Skin Tests
Reg. No./Substance:
0/Allergens; 37341-29-0/Immunoglobulin E

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