| The diagnosis and management of Kawasaki disease. | |
| | |
MedLine Citation:
|
PMID: 15790316 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Kawasaki disease (KD) is a systemic vasculitis of childhood with a predilection for the coronary arteries. It is the predominant cause of paediatric acquired heart disease in developed countries. The aetiology of KD remains unknown and consequently there is no diagnostic test. The diagnosis is made using a constellation of clinical criteria that in isolation have poor sensitivity and specificity. Early treatment prevents overt coronary artery damage in the majority of children. The long-term effects of childhood KD on later cardiovascular health remain unknown. A recent study showed that treatment of KD in Australia is suboptimal, with late diagnosis occurring in approximately half of the cases and an unacceptably high incidence of acute cardiac involvement. These guidelines highlight the difficulties in the diagnosis of KD and offer some clues that may assist early recognition of this important paediatric disease. They also detail current treatment recommendations and the evidence on which they are based. Increased awareness of the epidemiology and spectrum of the clinical presentation of KD is essential for early recognition and optimal management. |
| | |
Authors:
|
J Royle; D Burgner; N Curtis |
Related Documents
:
|
997056 - Treatment of uncontrolled hypertension by therapeutic renal infarction. 3208216 - Sphenoethmoidal sinusitis complicated by cavernous sinus thrombosis and pontocerebellar... 19593116 - Acute myocardial ischemia in a patient with heterozygous alpha-2-plasmin inhibitor defi... 18831296 - Sternal wound infections. 9342136 - Electroconvulsive therapy in patients with aortic stenosis. 16928496 - Eleven-year single-center experience with the ats open pivot bileaflet heart valve. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Journal of paediatrics and child health Volume: 41 ISSN: 1034-4810 ISO Abbreviation: J Paediatr Child Health Publication Date: 2005 Mar |
Date Detail:
|
Created Date: 2005-03-25 Completed Date: 2005-07-07 Revised Date: 2007-09-24 |
Medline Journal Info:
|
Nlm Unique ID: 9005421 Medline TA: J Paediatr Child Health Country: Australia |
Other Details:
|
Languages: eng Pagination: 87-93 Citation Subset: IM |
Affiliation:
|
Department of General Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anti-Inflammatory Agents, Non-Steroidal
/
therapeutic use* Aspirin / therapeutic use* Child, Preschool Female Humans Immunoglobulins, Intravenous* Infant Male Mucocutaneous Lymph Node Syndrome* / diagnosis, drug therapy, physiopathology |
| Chemical | |
Reg. No./Substance:
|
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Immunoglobulins, Intravenous; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Architecture of bacterial replication initiation complexes: orisomes from four unrelated bacteria.
Next Document: Airway gene therapy and cystic fibrosis.