Document Detail


The diagnosis of left ventricular outflow tract obstruction in hypertrophic cardiomyopathy.
MedLine Citation:
PMID:  22948303     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Hypertrophic cardiomyopathy is a prevalent genetic disease characterized by left ventricular hypertrophy, presenting dynamic obstruction of outflow tract with subaortic gradient happening at rest in 30% of the cases. It is attributed to the intricate interaction between the anterior mitral leaflet, the interventricular septum and altered flow vectors generated in left ventricle along with changes in outflow tract geometry. Mitral regurgitation in varying degrees is found with or without association with structural deformities of the valve apparatus. The exercise echocardiogram evidences latent obstruction easily induced by exercise in 60 to 75% of non-obstructive forms. The determination of the gradient under this condition must be considered in routine investigation of patients with mild or no obstruction at rest. The evaluation of hypertrophic cardiomyopathy incorporates methods based on the ultrasound image, which, along with MRI, allow recognizing ventricular obstruction generating mechanisms, thus facilitating the diagnosis and management of obstructive and latent obstructive forms.
Authors:
Beatriz Piva E Mattos; Marco Antonio Rodrigues Torres; Taiane Francieli Rebelatto; Melina Silva de Loreto; Fernando Luís Scolari
Related Documents :
19809203 - Acute myocardial infarction: the enduring challenge for cardiac protection and survival.
8504573 - One-year prognosis in patients hospitalized with a history of unstable angina pectoris.
10520783 - Prediction of functional recovery of viable myocardium after delayed revascularization ...
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Arquivos brasileiros de cardiologia     Volume:  99     ISSN:  1678-4170     ISO Abbreviation:  Arq. Bras. Cardiol.     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-9-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421031     Medline TA:  Arq Bras Cardiol     Country:  -    
Other Details:
Languages:  ENG; POR     Pagination:  665-675     Citation Subset:  -    
Affiliation:
Serviço de Cardiologia, Hospital de Clínicas de Porto Alegre.
Vernacular Title:
O diagnóstico da obstrução da via de saída do ventrículo esquerdo na cardiomiopatia hipertrófica.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Farming, Reported Pesticide Use, and Prostate Cancer.
Next Document:  Co-expression of AtbHLH17 and AtWRKY28 confers resistance to abiotic stress in Arabidopsis.