Document Detail


The diagnosis of Horner's syndrome. Use and limitations of the cocaine test.
MedLine Citation:
PMID:  3723131     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We prospectively studied the value of the cocaine test in the diagnosis of Horner's syndrome, by performing the test in 20 control subjects and in 20 patients with a provisional diagnosis of Horner's syndrome. Photographic testing of the darkness reflex of the pupil was used as an independent criterion of oculosympathetic dysfunction, and confirmed the diagnosis in 12 of the 20 patients. A mydriatic response to cocaine that was at least 1.0 mm less than in the unaffected eye occurred only with Horner's syndrome (7 patients). On the other hand, if the difference is smaller than 1.0 mm the chance that the patient does not have Horner's syndrome is only around 60%. There was no relationship between the magnitude of the response to cocaine and the site of the lesion in the sympathetic system.
Authors:
H L Van der Wiel; J Van Gijn
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  73     ISSN:  0022-510X     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  1986 May 
Date Detail:
Created Date:  1986-07-25     Completed Date:  1986-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  311-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Cocaine / diagnostic use*
Horner Syndrome / diagnosis*,  physiopathology
Humans
Iris / innervation
Middle Aged
Photography
Pupil
Sympathetic Nervous System / physiopathology
Chemical
Reg. No./Substance:
50-36-2/Cocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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