| The diabetic foot and leg: combined He-Ne and infrared low-intensity lasers improve skin blood perfusion and prevent potential complications. A prospective study on 30 Egyptian patients. | |
| | |
MedLine Citation:
|
PMID: 21455785 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The objective of this study was to examine skin blood flow in diabetic patients having disease-related skin lesions, and to evaluate possible improvement imposed by low-intensity laser therapy (LILT) as a new treatment modality. Thirty patients (in addition to 15 controls receiving conventional treatment = group II and 15 others receiving no treatment = group III) having diabetes-related skin lesions were tested for skin blood flow by laser Doppler flowmetry. Group I patients received LILT by a specified dosimetry. This was by combined uniform He-Ne and infrared lasers delivered by a scanner over the affected area. This study used a paired t test to determine the significance of blood flow recovery after treatment within each group while Independent t test compared results between the three groups. The level of significance was p < 0.05. The most frequently detected diabetes specific skin lesions were dryness, nail changes, hair loss, infections, itching, and frank eczema-like reactions, mostly in combinations (76%). This pattern appears specific for Egyptians as it is different from data registered in foreign literature. The minimum perfusion flow improved from 16.45 before LILT to 25.94 after, while maximum flow recovered from 32.91 to 48.47 and basal perfusion changed from 24.68 to 34.84 blood perfusion units. The percentage change in perfusion values was 23.17. All these were statistically significant. The study demonstrates that diabetes-linked skin lesions have a special pattern in Egyptians and are apparently caused by deranged skin blood flow .The deficit is measurable by laser flowmetry and can be partially reversed by LILT. |
| | |
Authors:
|
Gamal M Saied; Ragia M Kamel; Awatif M Labib; Mohamed T Said; Abir Z Mohamed |
Related Documents
:
|
17161765 - Nitric oxide release is impaired in hypertensive individuals with familial history of s... 10779015 - Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by l-argin... 864605 - Vasodilation due to urokinase in the canine femoral circulation. 9678785 - Measurement of the time course of peripheral vasoactivity: results in cigarette smokers. 386155 - Assessment of brescia-cimino fistula blood flow rates in pediatric patients. 620495 - Skeletal blood flow in paget's disease of bone and its response to calcitonin therapy. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-4-1 |
Journal Detail:
|
Title: Lasers in medical science Volume: - ISSN: 1435-604X ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-4-1 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8611515 Medline TA: Lasers Med Sci Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Departments of Internal Medicine and General Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt, gamal44@hotmail.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Role of Matrix Metalloproteinases and Therapeutic Benefits of Their Inhibition in Spinal Cord Injury...
Next Document: Effectiveness of various thermal ablation techniques for the treatment of nodular thyroid disease-co...