Document Detail

The developmental toxicity of 1-methyl-3-octylimidazolium bromide on Daphnia magna.
MedLine Citation:
PMID:  18442076     Owner:  NLM     Status:  MEDLINE    
The developmental toxicity of 1-methyl-3-octylimidazolium bromide ([C(8)mim]Br) on Daphnia magna was investigated. The 24 and 48 h LC(50) values for [C(8)mim]Br in D. magna were 1.99 and 0.95 mg/L, respectively. A series of multigenerational toxicity tests were then used to explore [C(8)mim]Br effects in D. magna. [C(8)mim]Br significantly inhibited the body lengths of the F0 and F1 1st generations. After 21 days of exposure, [C(8)mim]Br lowered the reproductive ability of the F0 and F1 1st generations. In F1 3rd generation, 21 days of [C(8)mim]Br exposure prolonged the time to bear the first egg and the time to the first brood compared with the control, but the number of first-brood offspring and the number of broods produced by these animals were reduced. After the recovery period all the reproductive parameters returned to normal in F1 1st generation except for the number of broods. The dead neonates increased with prolonged exposure and increasing concentrations, and the dead neonates of the F1 3rd generation went far beyond that of the F1 1st and F0 generations. The intrinsic rate of natural increase (r) values of the three D. magna generations significantly decreased after exposure to higher concentrations of [C(8)mim]Br compared with control groups. Collectively, these results suggest that [C(8)mim]Br exerts a toxic effect on the development of D. magna. This study also highlights the importance of systematically evaluating the potential effects of aquatic ecosystems of ionic liquids that may be released into bodies of water.
Yan-Rui Luo; Xiao-Yu Li; Xiao-Xiao Chen; Bang-Jun Zhang; Zhen-Jun Sun; Jian-Ji Wang
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental toxicology     Volume:  23     ISSN:  1522-7278     ISO Abbreviation:  Environ. Toxicol.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-10     Completed Date:  2009-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100885357     Medline TA:  Environ Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  736-44     Citation Subset:  IM    
Copyright Information:
2008 Wiley Periodicals, Inc.
College of Resources and Environmental Sciences, China Agricultural University, Beijing 100094, China.
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MeSH Terms
Animals, Newborn
Body Size / drug effects*,  physiology
Daphnia / drug effects*,  growth & development,  physiology*
Imidazoles / metabolism,  toxicity*
Ionic Liquids / metabolism,  toxicity
Reproduction / drug effects,  physiology
Time Factors
Toxicity Tests
Water Pollutants, Chemical / metabolism,  toxicity*
Reg. No./Substance:
0/1-methyl-3-octylimidazolium bromide; 0/Imidazoles; 0/Ionic Liquids; 0/Water Pollutants, Chemical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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