| The developmental origin of adolescent alcohol use: findings from the Mater University Study of Pregnancy and its outcomes. | |
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MedLine Citation:
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PMID: 18639392 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: It is unclear whether fetal alcohol exposure contributes to alcohol use in adolescence. In this study, we examine the association between maternal alcohol use in pregnancy and adolescents' drinking patterns at age 14. METHODS: The association of maternal alcohol exposure with early drinking was examined in 4363 adolescents taking part to the Mater University Study of Pregnancy (MUSP) and its outcomes, a population based birth cohort study commenced in Brisbane (Australia) in 1981. Mothers and children were followed up at birth, 5 and 14 years after the initial interview. Maternal alcohol use was assessed before and during pregnancy and at the 5 years follow-up. Adolescents' alcohol use was assessed at child age 14. RESULTS: In multivariable analysis those born of mothers who consumed 3+ glasses during pregnancy were at increased risk to report drinking 3+ glasses compared with those whose mothers reported no drinking or drinking up to 2 glasses. Comparisons controlling for drinking before pregnancy and at age 5 found the averaged odds ratio of maternal drinking in pregnancy on risk of reporting alcohol consumption of 3 and more glasses at age 14 was 2.74 (CI 1.70, 4.22). CONCLUSION: Our study suggests that they maybe a biological origin of early drinking. Further studies are needed to better disentangle the nature of the association and the role of other possible confounding factors. |
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Authors:
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Rosa Alati; Alexandra Clavarino; Jake M Najman; Michael O'Callaghan; William Bor; Abdullah Al Mamun; Gail M Williams |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-07-17 |
Journal Detail:
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Title: Drug and alcohol dependence Volume: 98 ISSN: 0376-8716 ISO Abbreviation: Drug Alcohol Depend Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-09-03 Completed Date: 2009-01-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7513587 Medline TA: Drug Alcohol Depend Country: Ireland |
Other Details:
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Languages: eng Pagination: 136-43 Citation Subset: IM |
Affiliation:
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School of Population Health, The University of Queensland, QLD, Australia. r.alati@sph.uq.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Alcohol Drinking / adverse effects*, epidemiology* Alcoholism / epidemiology* Cohort Studies Female Fetal Alcohol Syndrome / epidemiology* Humans Longitudinal Studies Male Pregnancy Prenatal Exposure Delayed Effects / epidemiology* Queensland Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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