Document Detail


The development of the fetal eye: in utero ultrasonographic measurements of the vitreous and lens.
MedLine Citation:
PMID:  7784367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our objective was to establish nomograms for fetal eye measurements from 12 weeks' gestation by using transvaginal and transabdominal high-resolution ultrasound techniques. A prospective cross-sectional study was performed on 450 normal singleton pregnancies between 12 and 37 weeks' gestation. Vitreous and lens circumferences were measured by transvaginal ultrasonography until 17 weeks, and by abdominal ultrasound between 18 and 37 weeks' gestation. Regression analyses were used to create nomograms, and several transformations were done to obtain linearity. Eye measurements of 12 fetuses at risk for ocular disturbances were plotted on the constructed nomograms. Linear relationships were fitted between vitreous (r2 = 0.79) and lens (r2 = 0.88) circumferences and gestational age. In addition, there was a significant correlation between these measurements and the biparietal diameter. Data of the fetuses at risk showed that disturbances in ocular growth were associated mainly with abnormal cerebral development. These normative data may be helpful in the prenatal diagnosis of suspected congenital syndromes that include, among their manifestations, ocular growth disturbances such as microphthalmos and anophthalmos.
Authors:
R Achiron; Z Gottlieb; Y Yaron; M Gabbay; U Gabbay; S Lipitz; S Mashiach
Related Documents :
19830377 - Morphometry of the gallbladder during the fetal period.
1418127 - Prenatal ultrasonic prediction of autopsy-proven pulmonary hypoplasia.
11447937 - Human foetal sacral length measurement for the assessment of foetal growth and developm...
11339927 - Influence of gestational age and maternal height on fetal femur length calculations.
19732887 - A short period of ejaculatory abstinence before intrauterine insemination is associated...
20214437 - Maternal cortisol in late pregnancy and hypothalamic-pituitary-adrenal reactivity to ps...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  15     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-07-20     Completed Date:  1995-07-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  155-60     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cross-Sectional Studies
Eye / embryology*,  ultrasonography
Female
Fetal Organ Maturity / genetics
Humans
Lens, Crystalline / embryology*,  ultrasonography
Pregnancy
Prospective Studies
Regression Analysis
Ultrasonography, Prenatal*
Vitreous Body / embryology*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Fetal erythroblasts from maternal blood identified with 2,3-bisphosphoglycerate (BPG) and in situ hy...
Next Document:  Oligohydramnios with amnio-chorionic separation at 15-16 weeks' gestation.