Document Detail

The development of the MCH system.
MedLine Citation:
PMID:  19647770     Owner:  NLM     Status:  MEDLINE    
Although a great deal is published on the MCH neurons, very few works were devoted to the study of their development. However, existing literature points out two important traits: first, these neurons differentiate a MCH phenotype very early in all species studied so far, which might suggest a role for the MCH peptide during development; second, in the rat, birth date greatly influence the phenotype of MCH neurons. At least two sub-populations were described on the basis of their chemical phenotype, projection pattern and birth date. The understanding of processes involved in the differentiation of these sub-populations may help understand the medio-lateral differentiation of the tuberal hypothalamus.
P Y Risold; S Croizier; K Legagneux; F Brischoux; D Fellmann; B Griffond
Publication Detail:
Type:  Journal Article; Review     Date:  2009-08-06
Journal Detail:
Title:  Peptides     Volume:  30     ISSN:  1873-5169     ISO Abbreviation:  Peptides     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-19     Completed Date:  2010-01-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008690     Medline TA:  Peptides     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1969-72     Citation Subset:  IM    
Universit?? de Franche-Comt??, Besan??on, France.
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MeSH Terms
Cell Differentiation* / genetics,  physiology
Hypothalamic Hormones / genetics,  metabolism,  physiology*
Melanins / genetics,  metabolism,  physiology*
Neurons / cytology,  metabolism*
Pituitary Hormones / genetics,  metabolism,  physiology*
Reg. No./Substance:
0/Hypothalamic Hormones; 0/Melanins; 0/Pituitary Hormones; 67382-96-1/melanin-concentrating hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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