Document Detail

The detection of tremor during slow alternating movements performed by patients with early Parkinson's disease.
MedLine Citation:
PMID:  14666394     Owner:  NLM     Status:  MEDLINE    
The present study demonstrates that tremor can be detected during slow alternating movements (SAM) performed by patients with early Parkinson's disease (PD) and that its relative amplitude is strongly correlated with patients' rest and postural hand tremor amplitudes (Rho=0.80 and 0.61, respectively, P<0.05). However, the tremor detected during SAM did not influence the accuracy of patients because of its relatively low amplitude. These results imply that the presence of tremor during movement is not restricted to advanced PD, but can also be detected in patients with early PD having relatively low amplitude tremor. Evidence that the tremor detected at rest, during posture and during voluntary movement share similar or overlapping neural substrates is also presented.
Christian Duval; Abbas F Sadikot; Michel Panisset
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2003-12-10
Journal Detail:
Title:  Experimental brain research     Volume:  154     ISSN:  0014-4819     ISO Abbreviation:  Exp Brain Res     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-01-21     Completed Date:  2004-05-12     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0043312     Medline TA:  Exp Brain Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  395-8     Citation Subset:  IM    
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MeSH Terms
Age of Onset
Aged, 80 and over
Arm / innervation,  physiopathology
Disease Progression
Middle Aged
Movement / physiology*
Muscle Contraction / physiology
Muscle, Skeletal / innervation,  physiopathology
Parkinson Disease / diagnosis,  physiopathology*
Reaction Time / physiology
Tremor / diagnosis,  physiopathology*

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