| The detection threshold for extremely low frequency magnetic fields may be below 1000 nT-Hz in mice. | |
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MedLine Citation:
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PMID: 21381048 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Previous experiments with mice have shown that a repeated 1 h daily exposure to an ambient magnetic field shielded environment induces analgesia (anti-nociception). This shielding reduces ambient static and extremely low frequency magnetic fields (ELF-MF) by approximately 100 times for frequencies below 120 Hz. To determine the threshold of ELF-MF amplitude that would attenuate or abolish this effect, 30 and 120 Hz magnetic fields were introduced into the shielded environment at peak amplitudes of 25, 50, 100 and 500 nT. At 30 Hz, peak amplitudes of 50, 100, and 500 nT attenuated this effect in proportion to the amplitude magnitude. At 120 Hz, significant attenuation was observed at all amplitudes. Exposures at 10, 60, 100, and 240 Hz with peak amplitudes of 500, 300, 500, and 300 nT, respectively, also attenuated the induced analgesia. No exposure abolished this effect except perhaps at 120 Hz, 500 nT. If the peak amplitude frequency product was kept constant at 6000 nT-Hz for frequencies of 12.5, 25, 50, and 100 Hz, the extent of attenuation was constant, indicating that the detection mechanism is dependent on the nT-Hz product. A plot of effect versus the induced current metric nT-Hz suggests a threshold of ELF-MF detection in mice at or below 1000 nT-Hz. Bioelectromagnetics. © 2011 Wiley-Liss, Inc. |
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Authors:
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Frank S Prato; Dawn Desjardins-Holmes; Lynn D Keenliside; Janice M Demoor; John A Robertson; Robert Z Stodilka; Alex W Thomas |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-4 |
Journal Detail:
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Title: Bioelectromagnetics Volume: - ISSN: 1521-186X ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8008281 Medline TA: Bioelectromagnetics Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Bioelectromagnetics Group, Imaging Program, Lawson Health Research Institute, London, Ontario, Canada; Department of Imaging, St. Joseph's Health Care, London, Ontario, Canada; Department of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada. prato@lawsonimaging.ca. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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