Document Detail


The detection of specific IgM antibodies following infection with rubella virus.
MedLine Citation:
PMID:  1150889     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A gel filtration technique using Sephadex G-200 has been used for the detection of specific IgM in sera from (a) 45 cases of clinical rubella in which diagnostic rises of rubella haemagglutination-inhibiting (HAI) antibody could be demonstrated; (b) 70 cases with clinical evidence of rubella in which a rising titre could not be demonstrated because the first serum sample already had high titre HAI antibodies; and (c) 100 patients in whom rubella was not suspected. The results indicate that the high specificity and sensitivity of the method described make it an appropriate technique for use in the routine diagnosis of acquired rubella.
Authors:
J R Pattison; J E Mace
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  28     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1975 May 
Date Detail:
Created Date:  1975-11-06     Completed Date:  1975-11-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  377-82     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Viral / analysis*
Chromatography, Gel
Hemagglutination Inhibition Tests
Humans
Immunoglobulin M / analysis*
Rubella / diagnosis,  immunology*
Rubella virus / immunology
Chemical
Reg. No./Substance:
0/Antibodies, Viral; 0/Immunoglobulin M
Comments/Corrections

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