| The dentate nucleus in children: normal development and patterns of disease. | |
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MedLine Citation:
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PMID: 20107778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The dentate nuclei lie deep within the cerebellum and play a vital role in the pathways involved in fine motor control and coordination. They are susceptible to a variety of diseases. Some pathological processes preferentially affect the dentate nuclei, while concomitant basal ganglia or white matter involvement can be a striking finding in others. A familiarity with the normal appearance of the dentate nuclei at different ages in combination with the radiological distribution of pathology in the brain allows the paediatric radiologist to develop a logical approach to the interpretation of MR imaging of these deep cerebellar nuclei. In this article we review the normal appearance and MR features of the dentate nuclei, including changes that are seen with myelination. We describe the specific imaging characteristics of childhood diseases that involve the dentate nuclei, and develop a systematic approach to the differential diagnosis of dentate nucleus abnormalities on MR imaging. |
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Authors:
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Aoife McErlean; Khaled Abdalla; Veronica Donoghue; Stephanie Ryan |
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Publication Detail:
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Type: Journal Article Date: 2010-01-28 |
Journal Detail:
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Title: Pediatric radiology Volume: 40 ISSN: 1432-1998 ISO Abbreviation: Pediatr Radiol Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-09 Completed Date: 2010-05-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0365332 Medline TA: Pediatr Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 326-39 Citation Subset: IM |
Affiliation:
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Radiology Department, Children's University Hospital, Dublin 1, Ireland. aoife@mcerlean.cc |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aging
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pathology* Cerebellar Diseases / pathology* Cerebellar Nuclei / pathology* Child, Preschool Female Humans Infant Infant, Newborn Male |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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