Document Detail


A delivery circuit for normothermic reperfusion model.
MedLine Citation:
PMID:  10063789     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to facilitate the introduction and assessment of Injectio Radix Ginseng Compositae in normothermic reperfusion model, a simplified delivery circuit is described herein. The circuit added mainly a venous reservoir collecting Injectio Radix Ginseng Compositae with cardiopulmonary bypass. Injectio Radix Ginseng Compositae was pumped into the ascending aorta of the animal after mixing with cardioplegia in the venous reservoir. The circuit was acceptable in terms of price by most inland medical laboratories. Perfusion as well as biochemical results monitored were satisfactory. Significant difference was noted between the average damage rates of the reperfused myocardial mitochondria in groups by ultrastructural analysis (70.12 +/- 2.56% vs. 25.33 +/- 17.62%, p = 0.023). No complications associated with perfusion technique occurred in either group. The circuit could offer a constant arterial perfusion, and was proved to be simple, safe and effective in cohort.
Authors:
S M Yuan; Q Wang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Kaohsiung journal of medical sciences     Volume:  15     ISSN:  1607-551X     ISO Abbreviation:  Kaohsiung J. Med. Sci.     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-03-16     Completed Date:  1999-03-16     Revised Date:  2006-08-28    
Medline Journal Info:
Nlm Unique ID:  100960562     Medline TA:  Kaohsiung J Med Sci     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  8-11     Citation Subset:  IM    
Affiliation:
Department of Cardiothoracic Surgery, 254 Hospital of Tianjin, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Myocardial Reperfusion Injury / prevention & control*
Panax / therapeutic use*
Phytotherapy*
Plants, Medicinal*

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