Document Detail


A decade of clinical trial developments in postmyocardial infarction, congestive heart failure, and sustained ventricular tachyarrhythmia patients: from CAST to AVID and beyond. Cardiac Arrhythmic Suppression Trial. Antiarrhythmic Versus Implantable Defibrillators.
MedLine Citation:
PMID:  9727666     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Multiple trials using antiarrhythmic drugs, pharmacologic therapy, and implantable cardioverter defibrillators have been performed in an attempt to improve survival in patients: (1) postmyocardial infarction; (2) with congestive heart failure, with and without nonsustained ventricular tachycardia; and (3) with sustained ventricular tachycardia and those who have survived an out-of-hospital cardiac arrest. This article reviews some of the key findings and limitations of completed and ongoing trials. We also make recommendations for the current treatment of such patients based on the results of these trials.
Authors:
G V Naccarelli; D L Wolbrette; J T Dell'Orfano; H M Patel; J C Luck
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of cardiovascular electrophysiology     Volume:  9     ISSN:  1045-3873     ISO Abbreviation:  J. Cardiovasc. Electrophysiol.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-11-20     Completed Date:  1998-11-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9010756     Medline TA:  J Cardiovasc Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  864-91     Citation Subset:  IM    
Affiliation:
Section of Cardiology and Cardiovascular Center, Penn State University College of Medicine, Hershey, USA.
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Antagonists / therapeutic use
Anti-Arrhythmia Agents / therapeutic use
Clinical Trials as Topic
Defibrillators, Implantable
Heart Failure / therapy*
Humans
Myocardial Infarction / therapy*
Tachycardia, Ventricular / therapy*
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Anti-Arrhythmia Agents
Comments/Corrections
Comment In:
J Cardiovasc Electrophysiol. 1999 Mar;10(3):420-1   [PMID:  10210508 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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