Document Detail

On the death of Kentuckian Charles Floyd, August 20, 1804--the only casualty of the Lewis and Clark expedition: a solution to a 200-year-old medical mystery.
MedLine Citation:
PMID:  17941423     Owner:  NLM     Status:  MEDLINE    
As a member of the Lewis and Clark Expedition, Charles Floyd was the first United States soldier to die west of the Mississippi River. He was among his companions and developed the sudden onset of abdominal pain and was dead the next day. The most common medical opinion for cause of death has been acute appendicitis. However a new edition of his journal reveals signs and symptoms previously overlooked suggesting a genetically determined metabolic etiology, which is explored in this report to the conclusion that he died from acute intermittent porphyria.
Charles L Dannaher
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Publication Detail:
Type:  Biography; Case Reports; Historical Article; Journal Article    
Journal Detail:
Title:  The Journal of the Kentucky Medical Association     Volume:  105     ISSN:  0023-0294     ISO Abbreviation:  J Ky Med Assoc     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-10-18     Completed Date:  2007-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505615     Medline TA:  J Ky Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  445-51     Citation Subset:  IM    
Consultants in Blood Disorders and Cancer, Louisville, Kentucky, USA.
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MeSH Terms
Expeditions / history*
Famous Persons
Fatal Outcome
History, 19th Century
Military Personnel / history*
Porphyria, Acute Intermittent / diagnosis*,  genetics
Records as Topic
Personal Name Subject
Personal Name Subject:
Charles Floyd

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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