Document Detail


A damage limitation exercise.
MedLine Citation:
PMID:  21364567     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Cellular senescence is a potent tumour suppressor mechanism that is often accompanied by activation of DNA damage response (DDR) signalling and marked heterochromatinization. Senescence-associated heterochromatin is now shown to limit DDR, thus reducing apoptosis and promoting survival of senescent cells.
Authors:
Andrejs Ivanov; Peter D Adams
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nature cell biology     Volume:  13     ISSN:  1476-4679     ISO Abbreviation:  Nat. Cell Biol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890575     Medline TA:  Nat Cell Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  193-5     Citation Subset:  IM    
Affiliation:
Institute of Cancer Sciences, University of Glasgow, Cancer Research UK Beatson Labs, Garscube estate, Switchback road, Bearsden, Glasgow, G61 1BD, U.K. p.adams@beatson.gla.ac.uk.
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