| A damage limitation exercise. | |
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MedLine Citation:
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PMID: 21364567 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cellular senescence is a potent tumour suppressor mechanism that is often accompanied by activation of DNA damage response (DDR) signalling and marked heterochromatinization. Senescence-associated heterochromatin is now shown to limit DDR, thus reducing apoptosis and promoting survival of senescent cells. |
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Authors:
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Andrejs Ivanov; Peter D Adams |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nature cell biology Volume: 13 ISSN: 1476-4679 ISO Abbreviation: Nat. Cell Biol. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890575 Medline TA: Nat Cell Biol Country: England |
Other Details:
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Languages: eng Pagination: 193-5 Citation Subset: IM |
Affiliation:
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Institute of Cancer Sciences, University of Glasgow, Cancer Research UK Beatson Labs, Garscube estate, Switchback road, Bearsden, Glasgow, G61 1BD, U.K. p.adams@beatson.gla.ac.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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