Document Detail

The daily profile of ventricular premature beats in the patients with ischemic heart disease.
MedLine Citation:
PMID:  2439718     Owner:  NLM     Status:  MEDLINE    
To clarify factors affecting the prevalence of ventricular premature contraction (VPC) in patients with stable ischemic heart disease, daily profiles of VPC prevalence were studied in 92 patients using continuous 24-hour electrocardiographic recordings. VPCs in patient groups with effort angina and inferior infarction showed similar daily profiles. However, a significant relationship between VPC prevalence and heart rate was observed in inferior infarction group, while patients with resting angina exhibited another relationship between the two parameters. Higher prevalence rate of VPCs in the early morning in patients with resting angina suggested the contribution of cardiac autonomic nerve activity to the increased frequency of VPCs, while constant frequency of VPCs during the day in anterior infarction group provided no influences on heart rate, effort, and autonomic nerve activity on the VPC prevalence. Age, sex, left ventricular ejection fraction, and nitrates and diltiazem used for the treatment of angina pectoris did not affect the daily profile of VPC prevalence in any patient groups. These results indicated that the clinical and pathophysiological differences of ischemic heart disease, even in stable patients, showed the different distribution of VPC prevalence within a day which is due, in part, to the varied activities of cardiac autonomic nerves.
D Saito; S Matsuno; S Haraoka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  51     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-08-04     Completed Date:  1987-08-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  208-16     Citation Subset:  IM    
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MeSH Terms
Angina Pectoris / drug therapy
Calcium Channel Blockers / therapeutic use
Cardiac Complexes, Premature / complications*,  epidemiology
Coronary Angiography
Coronary Disease / complications*,  drug therapy
Heart Rate
Middle Aged
Monitoring, Physiologic
Nitrates / therapeutic use
Stroke Volume
Reg. No./Substance:
0/Calcium Channel Blockers; 0/Nitrates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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