Document Detail

The cytopathology of mesothelioma.
MedLine Citation:
PMID:  294056     Owner:  NLM     Status:  MEDLINE    
Fifty-seven cases of mesothelioma from the Toronto General Hospital during the period 1965 to 1976 have been reviewed. Pleural effusions or ascites were present in 34 patients. The value of cytologic examination of effusion specimens was assessed, and the criteria for cytologic diagnosis were elucidated. It appears that patients with predominantly fibrous or sarcomatous mesothelioma were not prone to develop pleural effusions or ascites; few tumor cells, if any, from these mesotheliomas were exfoliated into effusions. Cytologic examinations of effusion specimens were positive in 12 of 14 cases of carcinomatous mesothelioma and in three of four cases of undifferentiated mesothelioma. However, only four of seven casee of benign mesothelioma (mostly epithelial type) showed positive results, as did two of four cases of sarcomatous mesothelioma. It appears that cytologic diagnosis of mesothelioma is more useful for the carcinomatous and undifferentiated types. The cytomorphologic features of the various types of mesothelioma are different, and by cytologic examination of effusion specimens, typing of mesothelioma is possible and correlates well with the histologic typing.
L C Tao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  23     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1979 May-Jun
Date Detail:
Created Date:  1980-03-24     Completed Date:  1980-03-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  209-13     Citation Subset:  IM    
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MeSH Terms
Ascitic Fluid / cytology*
Cell Nucleus / ultrastructure
Diagnosis, Differential
Mesothelioma / classification,  diagnosis*,  pathology
Middle Aged
Pleural Effusion / cytology*

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