Document Detail


A cytochemical section-bioassay for thyrotropin.
MedLine Citation:
PMID:  7229039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A cytochemical section-bioassay of thyrotropin has been developed which retains the sensitivity of the earlier segment-assay (10(-4) microunits/ml) and allows a considerable increase in the rate at which these within-animal bioassays can be done. The index of precision (n=23) was 0.11 +/- 0.06; intra-assay variation was 1.3%; inter-assay variation was 10.9 +/- 6%. Fiducial limits (p = 0.95) ranged from 65-150% to 78-127%. The system is also capable of detecting thyroid-stimulating immunoglobulins.
Authors:
J Chayen; D M Gilbert; W R Robertson; L Bitensky; G M Besser
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of immunoassay     Volume:  1     ISSN:  0197-1522     ISO Abbreviation:  J Immunoassay     Publication Date:  1980  
Date Detail:
Created Date:  1981-07-09     Completed Date:  1981-07-09     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8007167     Medline TA:  J Immunoassay     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-13     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aminopeptidases / metabolism
Animals
Antibodies
Antibody Specificity
Female
Guinea Pigs
Histocytochemistry
Luteinizing Hormone
Lysosomes / enzymology
Thyrotropin* / immunology,  pharmacology
Time Factors
Chemical
Reg. No./Substance:
0/Antibodies; 9002-67-9/Luteinizing Hormone; 9002-71-5/Thyrotropin; EC 3.4.11.-/Aminopeptidases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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