| The current role of PET-CT in the characterization of hepatobiliary malignancies. | |
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MedLine Citation:
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PMID: 19590618 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Surgery has become heavily dependent on accurate imaging in the assessment and treatment of suspected or confirmed intra-abdominal malignancy. Positron emission tomography-computed tomography (PET-CT) fuses uptake of a radiotracer combined with CT images to assess both functional tissue activity and anatomical detail. Since its introduction it has offered new ways of treating gastrointestinal cancers. METHODS: The review analyses the present literature regarding the use of PET-CT in the assessment, diagnosis, staging and treatment of hepatobiliary malignancies. RESULTS: PET-CT is widely used in pre-operative tumours staging for colorectal liver metastases. There is convincing data that it may also be applicable for neuroendocrine tumours, assessment of indeterminate pancreas lesions and clinical drug trials. PET-CT is of limited value in hepatocellular cancers, although new techniques in dual-tracer PET-CT may change this. CONCLUSION: Knowledge of the strengths and limitations of PET-CT is important for all surgeons managing cancer of the hepatobiliary system. More clinical data are required on PET-CT, particularly its effect on long-term survival in PET-CT-staged patients undergoing resection. |
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Authors:
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Ginseppe Garcea; Seok Ling Ong; Guy J Maddern |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: HPB : the official journal of the International Hepato Pancreato Biliary Association Volume: 11 ISSN: 1365-182X ISO Abbreviation: HPB (Oxford) Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-07-10 Completed Date: 2010-06-09 Revised Date: 2010-06-10 |
Medline Journal Info:
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Nlm Unique ID: 100900921 Medline TA: HPB (Oxford) Country: England |
Other Details:
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Languages: eng Pagination: 4-17 Citation Subset: - |
Affiliation:
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Department of Hepatobiliary and Upper Gastrointestinal Surgery, The Queen Elizabeth Hospital, Adelaide, SA, Australia. gg43@le.ac.uk |
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