Document Detail


The critical role of familiar urine odor in diminishing territorial aggression toward a castrated intruder in mice.
MedLine Citation:
PMID:  17150232     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sensory chemo-signals conveying information on sex and familiarity are important to the manifestation of aggressive behaviors in male mice. In this study, we examined the role of familiarity conveyed by urine odor in the induction of aggressive behavior using a resident-intruder paradigm. First, an intact ICR male mouse (resident) was grouped with a castrated DBA mouse (cage-mate) and a female ICR mouse to allow the resident mouse to establish its territory. The resident male showed vigorous aggression, not only toward intact male DBA intruders, but also toward unfamiliar castrated DBA mice (UFC). In contrast, the aggression was markedly reduced toward its castrated DBA cage-mate. Next, to reveal how residents discriminate their cage-mates from unfamiliar intruders, we examined whether urine odor affected this familiarity-related aggression. When part of the body surface of a UFC was swabbed with the urine of a resident's cage-mate, the resident attacked the UFC much less often. These results suggest that the information about familiarity conveyed by urine odor plays an important role in controlling the territorial aggression of a resident male mouse toward castrated intruders.
Authors:
Kayo Nakamura; Takefumi Kikusui; Yukari Takeuchi; Yuji Mori
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-12-05
Journal Detail:
Title:  Physiology & behavior     Volume:  90     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-05     Completed Date:  2007-04-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  512-7     Citation Subset:  IM    
Affiliation:
Laboratory of Veterinary Ethology, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aggression / physiology*
Analysis of Variance
Animals
Castration
Female
Male
Mice
Mice, Inbred ICR
Odors
Recognition (Psychology) / physiology*
Smell / physiology*
Statistics, Nonparametric
Territoriality*
Urine / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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