| A critical appraisal of the radiological evaluation of nephrocalcinosis. | |
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MedLine Citation:
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PMID: 17522474 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIM: The level of agreement concerning the diagnosis of nephrocalcinosis (NC) based on ultrasonography (US), computed tomography (CT) or kidney/ureter/bladder (KUB) X-ray was assessed. METHODS: Sequences of KUB+US+CT from 62 patients, 48 with at least one exam suggesting NC and 14 with pelvicalyceal calcifications (nephrolithiasis) were reviewed twice by 3 radiologists (firstly randomized and secondly presenting KUB+US+CT of each patient together). RESULTS: The intraobserver concordance varied from 76 to 90% for KUB, 77 to 85% for US and 82 to 89% for CT. There was a significant change in diagnosis between the 1st and 2nd reviews for observer 1 in KUB and CT, for observer 2 in US, but not for observer 3. Evaluating patients' exams together did not provide a better agreement. The highest sensitivity and specificity (92 and 89%, respectively) were only attained when 2 exams suggested NC diagnosis, being CT one of them. These enabled us to suggest that 33 out of 48 (62.5%) patients had NC (evidenced in US+CT+KUB (81.8%), US+CT (12.1%) or KUB+CT (6.1%). CONCLUSION: The low level of concordance renders the radiological diagnosis of NC difficult. Nephrocalcinosis should be confirmed by CT combined with either US or KUB. |
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Authors:
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Lara Cheidde; Sérgio Aron Ajzen; Cecilia Helena Tamer Langen; Dejaldo Christophalo; Ita Pfeferman Heilberg |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2007-05-22 |
Journal Detail:
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Title: Nephron. Clinical practice Volume: 106 ISSN: 1660-2110 ISO Abbreviation: Nephron Clin Pract Publication Date: 2007 |
Date Detail:
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Created Date: 2007-07-13 Completed Date: 2007-09-28 Revised Date: 2007-11-19 |
Medline Journal Info:
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Nlm Unique ID: 101159763 Medline TA: Nephron Clin Pract Country: Switzerland |
Other Details:
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Languages: eng Pagination: c119-24 Citation Subset: IM |
Copyright Information:
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Copyright 2007 S. Karger AG, Basel. |
Affiliation:
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Nephrology Division, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Child, Preschool Female Humans Male Metabolic Diseases / diagnosis, etiology Middle Aged Nephrocalcinosis / complications, radiography*, ultrasonography Observer Variation Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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