Document Detail

A critical appraisal of current management practices for infant regurgitation--recommendations of a working party.
MedLine Citation:
PMID:  9177975     Owner:  NLM     Status:  MEDLINE    
Regurgitation is a common manifestation in infants below the age of 1 year and a frequent reason of counselling of general practitioners and paediatricians. Current management starts with postural and dietary measures, followed by antacids and prokinetics. Recent issues such as an increased risk of sudden infant death in the prone sleeping position and persistent occult gastro-oesophageal reflux in a subset of infants receiving milk thickeners or thickened "anti-regurgitation formula" challenge the established approach. Therefore, the clinical practices for management of infant regurgitation have been critically evaluated with respect to their efficacy, safety and practical implications. The updated recommendations reached by the working party on the management of infant regurgitation contain five phases: (1 A) parental reassurance; (1 B) milk-thickening agents; (2) prokinetics; (3) positional therapy as an adjuvant therapy; (4 A) H2-blockers; (4 B) proton pump inhibitors; (5) surgery.
Y Vandenplas; D Belli; P Benhamou; S Cadranel; J P Cezard; S Cucchiara; C Dupont; C Faure; F Gottrand; E Hassall; H Heymans; C M Kneepkens; B Sandhu
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of pediatrics     Volume:  156     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-08-19     Completed Date:  1997-08-19     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  343-57     Citation Subset:  IM    
Academisch Zeckenhuis Kinderen, Vrije Universiteit Brussel, Brussels, Belgium.
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MeSH Terms
Antacids / therapeutic use
Antiemetics / therapeutic use
Case Management / standards*
Clinical Trials as Topic
Gastroesophageal Reflux / physiopathology,  therapy*
Health Education
Infant Food / standards
Practice Guidelines as Topic / standards*
Prone Position
Remission, Spontaneous
Sudden Infant Death / etiology
Treatment Outcome
Reg. No./Substance:
0/Antacids; 0/Antiemetics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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