Document Detail

The cranial base in anencephaly and microcephaly studied histologically.
MedLine Citation:
PMID:  7233332     Owner:  NLM     Status:  MEDLINE    
A histological microradiographical analysis was carried out on the cranial base removed at autopsy from three infants--two with microcephalia, one with anencephalia. The histological findings were compared with those from normal individuals of the same age. It was shown that a reduced size of the brain was accompanied by a change in the remodeling pattern of the internal as well as the external surface of the cranial base, leading to a flattening of the cranial base. The findings further suggest that the development of the brain influences the ossification of the chondrocranium.
B Melsen; F Melsen
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Teratology     Volume:  22     ISSN:  0040-3709     ISO Abbreviation:  Teratology     Publication Date:  1980 Dec 
Date Detail:
Created Date:  1981-07-09     Completed Date:  1981-07-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0153257     Medline TA:  Teratology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  271-7     Citation Subset:  IM    
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MeSH Terms
Anencephaly / pathology*
Bone Diseases, Developmental / pathology
Brain / pathology
Infant, Newborn
Microcephaly / pathology*
Skull / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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