Document Detail

The course of maturation of rod-mediated visual thresholds in infants.
MedLine Citation:
PMID:  10393066     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To measure the developmental course of infants' rod-mediated thresholds. METHODS: Thresholds for detecting stimuli (2 degrees diameter, 50 msec duration) presented at 10 degrees (parafoveal site) or 30 degrees (peripheral site) from a central fixation target were estimated using a preferential-looking method. Nine infants were tested at both stimulus positions at ages 10, 18, and 26 weeks. RESULTS: At 10 weeks, infants' thresholds at both sites were significantly higher than those of adults. The infants' average threshold at 10 degrees was 0.5 log unit higher than the infants' average threshold at 30 degrees. Adults' thresholds at the two sites were equal. Thresholds of all infants decreased with age until by age 26 weeks the parafoveal and peripheral thresholds were equal and were the same as those of adults. The rate of change of parafoveal thresholds was significantly faster than the rate of change of peripheral thresholds. CONCLUSIONS: Although postreceptoral factors cannot be ruled out, the results suggest that developmental increases in rod outer segment length and rhodopsin density account for most of the threshold changes during infancy.
R M Hansen; A B Fulton
Related Documents :
8125736 - Scotopic optokinetic nystagmus thresholds in 10-week-old infants.
16081126 - Achromatic contrast effects in infants: adults and 4-month-old infants show similar dev...
25249806 - Reexamining the risks of drinking-water nitrates on public health.
15234286 - Effect of cataract extraction on frequency doubling technology perimetry.
9825016 - Reliability of statistics on violent death and suicide in the former ussr, 1970-1990.
12416286 - Pacifier use and sudden infant death syndrome: should health professionals recommend pa...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  40     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-07-08     Completed Date:  1999-07-08     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1883-6     Citation Subset:  IM    
Department of Ophthalmology, Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Dark Adaptation
Fovea Centralis / physiology
Longitudinal Studies
Retinal Rod Photoreceptor Cells / physiology*
Sensory Thresholds / physiology
Visual Acuity / physiology*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The rhodopsin content of human eyes.
Next Document:  Modes of cardiovascular regulation during middle childhood.