Document Detail


The course of glaucoma during pregnancy: a retrospective case series.
MedLine Citation:
PMID:  16908810     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To better understand the course of glaucoma during pregnancy in women with preexisting disease. METHODS: Retrospective case series of 28 eyes of 15 women with glaucoma followed up during pregnancy. Data were analyzed for age, race/ethnicity, medications, glaucoma type, intraocular pressure (IOP), and visual fields before, during, and after pregnancy. RESULTS: In 16 (57.1%) of 28 eyes, IOP was stable during pregnancy, with no progression of visual field loss. In 5 eyes (17.9%), visual field loss progressed during pregnancy, while IOP remained stable or increased. In 5 eyes (17.9%), IOP increased during pregnancy, but there was no progression of visual field loss. In 2 eyes (7.1%), data were inconclusive because of medication noncompliance and preexisting severe visual field loss. Glaucoma medications were used by 13 of 15 patients to control glaucoma during pregnancy. The classes of medications used most frequently were beta-blockers, alpha2-adrenergic agents, cholinergic agents, and topical carbonic anhydrase inhibitors. CONCLUSIONS: The course of glaucoma during pregnancy is variable, and women must be monitored closely during pregnancy. Medications may be necessary to control IOP and to prevent vision loss during pregnancy.
Authors:
Stacey C Brauner; Teresa C Chen; B Thomas Hutchinson; Michael A Chang; Louis R Pasquale; Cynthia L Grosskreutz
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  124     ISSN:  0003-9950     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-15     Completed Date:  2006-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1089-94     Citation Subset:  AIM; IM    
Affiliation:
Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Disease Progression
Female
Glaucoma / physiopathology*
Humans
Intraocular Pressure / physiology
Pregnancy
Pregnancy Complications / physiopathology*
Retrospective Studies
Visual Fields / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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