| The cost-effectiveness of bimatoprost 0.03% in the treatment of glaucoma in adult patients--a European perspective. | |
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MedLine Citation:
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PMID: 16115174 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Glaucoma is a condition affecting one or both eyes with raised intraocular pressure (IOP). IOP should be reduced to prevent progression of visual field loss. This study investigates the cost-effectiveness of bimatoprost compared with latanoprost as first-line monotherapies in the treatment of glaucoma in Austria, Finland and France. On the basis of a single multicentre, randomised, investigator-masked controlled trial, a 6- and 12-month cost-effectiveness model was designed following the treatment recommendations from the European Glaucoma Society. Treatment changes due to insufficient IOP reduction and adverse events were included. The cost-effectiveness analysis showed that the need for adjunctive therapy was the major cost driver. On the basis of evidence from the randomised, investigator-masked clinical trial (RCT), the cost-effectiveness analysis found that bimatoprost was a cheaper and a more effective treatment strategy compared with latanoprost. This was true for all three countries and all IOP targets between 13 and 20 mmHg. The cost-effectiveness result may be generalised to a European setting and perspective. |
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Authors:
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E Tuil; A B Hommer; P B Poulsen; T L Christensen; P Buchholz; J Walt; S Holmstrom |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of clinical practice Volume: 59 ISSN: 1368-5031 ISO Abbreviation: Int. J. Clin. Pract. Publication Date: 2005 Sep |
Date Detail:
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Created Date: 2005-08-23 Completed Date: 2006-02-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9712381 Medline TA: Int J Clin Pract Country: England |
Other Details:
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Languages: eng Pagination: 1011-6 Citation Subset: IM |
Affiliation:
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CHNO des Quinze Vingts, Paris, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amides Antihypertensive Agents / adverse effects, economics*, therapeutic use Austria Chemotherapy, Adjuvant / economics Cloprostenol / analogs & derivatives Cost-Benefit Analysis Drug Costs Finland France Glaucoma / drug therapy* Humans Lipids / adverse effects, economics*, therapeutic use Models, Economic* Ophthalmic Solutions Prostaglandins F, Synthetic / adverse effects, economics, therapeutic use Randomized Controlled Trials as Topic |
| Chemical | |
Reg. No./Substance:
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0/Amides; 0/Antihypertensive Agents; 0/Lipids; 0/Ophthalmic Solutions; 0/Prostaglandins F, Synthetic; 0/bimatoprost; 130209-82-4/latanoprost; 40665-92-7/Cloprostenol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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