Document Detail

A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world.
MedLine Citation:
PMID:  22870564     Owner:  NLM     Status:  In-Process    
Vitamin D deficiency is a common health complication in patients with chronic kidney disease and can be treated with an abundance of classical and advanced pharmaceutics. However, the impact of bundling in dialysis clinics limits the use of the most optimal therapeutics and desired efficacy targets in end-stage renal disease patients. To address this issue, we investigated the benefits of adding a cost-effective antioxidant and vitamin D nutraceutical (MV-ONE, Nephrian Inc.) to patient regiments. This nutraceutical was used in an attempt to replete vitamin D levels and decrease inflammation that dialysis patients experience. Additionally, we investigated the potential of this therapy to reduce the need for erythropoietin-stimulating agents. Results indicate MV-ONE caused: (1) increases in 25-OH vitamin D (p = 0.0058), (2) decreases in ESA dose (p = 0.0475), and (3) no change in C-reactive protein (p = 0.3290). Overall, this suggests the addition of MV-ONE does benefit the vitamin D deficiency and anemia observed in ESRD patients.
John Larkin; Liza Bea; Amit Sharma
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nephrology news & issues     Volume:  26     ISSN:  0896-1263     ISO Abbreviation:  Nephrol News Issues     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-08-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8709753     Medline TA:  Nephrol News Issues     Country:  United States    
Other Details:
Languages:  eng     Pagination:  22-4, 26     Citation Subset:  N    
Pacific Renal Research Institute, Caldwell, Idaho, USA.
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