Document Detail

A cost-benefit analysis of the post-operative use of antibiotic ear drops following grommet insertion.
MedLine Citation:
PMID:  8763369     Owner:  NLM     Status:  MEDLINE    
A prospective randomized controlled study was carried out to investigate the effect of prophylactic antibiotic ear drops used for five days after bilateral grommet insertion. The average improvement in the hearing threshold was significantly better in ears in which there was an effusion (16 dB) compared with no effusion (9 dB). The drops had no significant effect upon grommet function at three months measured by blockage rates, extrusion rates or improvement in pure tone audiometry whether or not there was an effusion. The drops were not therefore cost-effective.
C R Pearson; M R Thomas; H J Cox; R J Garth
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  110     ISSN:  0022-2151     ISO Abbreviation:  J Laryngol Otol     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-10-15     Completed Date:  1996-10-15     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  527-30     Citation Subset:  AIM; IM    
Department of Otolaryngology, Royal Naval Hospital, Hants, UK.
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MeSH Terms
Audiometry, Pure-Tone
Auditory Threshold
Child, Preschool
Cost-Benefit Analysis
Dexamethasone / administration & dosage
Drug Therapy, Combination / economics*,  therapeutic use*
Framycetin / administration & dosage
Gramicidin / administration & dosage
Instillation, Drug
Middle Ear Ventilation*
Otitis Media with Effusion / prevention & control*,  surgery
Postoperative Period
Prospective Studies
Reg. No./Substance:
119-04-0/Framycetin; 1405-97-6/Gramicidin; 50-02-2/Dexamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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