Document Detail

The correlation of cytologic degree of differentiation of infiltrative ductal breast carcinoma and cytochemical activity of glucose-6-phosphate dehydrogenase.
MedLine Citation:
PMID:  9769735     Owner:  NLM     Status:  MEDLINE    
The semiquantitative cytochemical activity of glucose-6-phosphate dehydrogenase in imprints of surgical biopsies of 55 patients with invasive ductal breast carcinomas was compared to the cytologic degree of differentiation. All carcinomas cytologically designated as well differentiated had a low enzyme activity. Approximately half of moderately differentiated carcinomas were characterized with low score of enzyme activity and only 2 out of 26 poorly differentiated tumors had the low enzyme activity. The estimation of cytochemical activity of this enzyme may be valuable as the morphologic parameter for cytologic evaluation of malignant cells.
R Bokun; Z Tatomirović
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vojnosanitetski pregled. Military-medical and pharmaceutical review     Volume:  55     ISSN:  0042-8450     ISO Abbreviation:  Vojnosanit Pregl     Publication Date:    1998 Jul-Aug
Date Detail:
Created Date:  1998-11-13     Completed Date:  1998-11-13     Revised Date:  2008-01-09    
Medline Journal Info:
Nlm Unique ID:  21530700R     Medline TA:  Vojnosanit Pregl     Country:  YUGOSLAVIA    
Other Details:
Languages:  eng     Pagination:  369-72     Citation Subset:  IM    
Military Medical Academy, Institute of Pathology, Belgrade.
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MeSH Terms
Breast Neoplasms / enzymology,  pathology*
Carcinoma, Ductal, Breast / enzymology,  pathology*
Glucosephosphate Dehydrogenase / analysis*
Reg. No./Substance:
EC Dehydrogenase

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